BMD-08-peptide-01 BMD-10-abmuno BMD-07-01

Peptide Synthesis

化學合成之胜肽可用來製備抗體或作為蛋白質定量的標準品,應用在蛋白質功能與結構之基礎研究、胜肽藥物研發與臨床治療的應用研究等。

本公司提供多種合成量、純度及合成服務項目。

合成量:1-1000mg or >1000mg

純度:>Crude(50%)>Desalted(60%)>70%>75%>80%>85%>90%        >95%>98%
合成項目:

簡單的、複雜的

線性的、環狀的

長序列多肽,可至140個胺基酸

修飾多肽:

1.     N端修飾

2.     C端修飾

3.     特殊胺基酸

4.     螢光染料標記

5.     環肽

6.     磷酸化多肽

Item

Modification

N,C-terminal Modification

Acetylation (N-Terminal) ,HYNIC (N-Terminal),DTPA (N-Terminal),Formylation (N-Terminal), Fatty acid (N-Terminal),Myristic acid (N-Terminal),Palmytolyl (N-Terminal),Benzyloxycarbonylation(CBZ) , Amidation (C-Terminal),Succinylation (Suc, N-Terminal)

Special Amino acid

D-Arg, D-Cys, D-Asp, D-Asn, D-Glu, D-Gln, D-Ser, D-His, D-Thr, D-Trp, D-Leu,D-Ile, D-Met, D-Pro, D-Val , D-Phe, pGlu, Hyp, D-Lys, D-Tyr, D-Orn, Orn, Abu, Aib, (D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa, N-Methyl amino acid (Ala, Phe, Leu, Ile, Val, Gly, Met), Other amino acid, Dinitrobenzoylation (Lys), Lys(Me2), Phosphorylation (Tyr, Ser, Thr, single site),Tyr(SO3H2), Ser(octanoic acid)

Fluorescence/Dye labeling

Biotin (Lys in sequence), Biotin (N-Terminal, Y/N Ahx), Biotin (without Lys in sequence), FITC/5-FAM (N-Terminal, Y/N Ahx) ,Dansyl (N-Terminal, Y/N Ahx), MCA (N-Terminal), p-Nitroanilide(pNA, C-Terminal), AMC (C-Terminal)

Cyclic Peptide

Disulfide bridg 1nd ,Disulfide bridge 2nd ,Disulfide bridge 3rd, ,Amide cyclic (Side chain, end)

Quenched Fluorescent Peptide

Abz/ Tyr (3-NO2), EDANS/DABCYL

Multiple Antigenic Peptide System

Asymmetric 4 branches, Asymmetric 8 branches

Protein Conjugation

KLH , BSA

 

純度選擇

Recommended Purity

Applications

Peptide purity >75%

Peptide Array and Screening Studies

Polyclonal Antibodies

Immunogenic Identification

Mutation Screening

Sequence Optimization

ELISA Tests

Peptide purity >85%

Phosphorylation Studies

Semi-quantitative Enzyme-Substrate Studies

Non-quantitative Peptide Blocking Studies for Western blotting and Immunocytochemistry

In-vitro Bioassays

Cell Attachment Studies

Epitope Mapping

Coupling to Chromatography Resins for Affinity Purifications

Antibody- Antigen Interaction Studies

Antigenic Peptides in Immune Lymphocyte Assays

Peptide purity >95%

Quantitative Blocking and Competitive Inhibition Assays

Quantitative Receptor-Ligand Interaction Studies

Quantitative Phosphorylation Studies & Quantitative Proteolysis Studies

In-vivo Studies & In-vitro Bioassays

Generating Standard Curves

Reference Standards & Diagnostic Kits

NMR spectroscopy Studies &Crystallography

Peptide purity >98%

Clinical Trials & Drug Studies

SAR Studies

 

胺基酸對照表

胺基酸

縮寫

Alanine

Ala

A

Arginine

Arg

R

Asparagine

Asn

N

Aspartic Acid

Asp

D

Cysteine

Cys

C

Glutamine

Gln

Q

Glutamic Acid

Glu

E

Glycine

Gly

G

Histidine

His

H

Isoleucine

Ile

I

Leucine

Leu

L

Lysine

Lys

K

Methionine

Met

M

Phenylalanine

Phe

F

Proline

Pro

P

Serine

Ser

S

Threonine

Thr

T

Tryptophan

Trp

W

Tyrosine

Tyr

Y

Valine

Val

V